Which vaccine can have a skin test associated with it?

The correct response is the Tuberculosis (TB) vaccine. The reason for this is that the TB vaccine, specifically the Bacillus Calmette-Guérin (BCG) vaccine, is associated with the Mantoux test, which is a skin test used to determine if a person has been infected with the tuberculosis bacteria. This test involves intradermal injection of a purified protein derivative (PPD) and reading the induration (swelling) after a specified timeframe to assess the immune response.

In contrast, the flu vaccine, measles vaccine, and hepatitis B vaccine do not involve skin testing as part of their screening or administration process. They are typically evaluated based on vaccination history or specific immunological blood tests rather than skin reactions. Thus, only the tuberculosis vaccine directly correlates with a skin test mechanism that is used for screening and has a critical role in public health.